Here are some extremely helpful keyboard shortcut keys for Visual Studio 2008. You probably know most, but some you won't know. For instance, did you know that Ctrl+. is the same as Sift+Alt+F10?
Note: Some of the shortcuts won't work in all environment configurations (web, C#, etc).
To use, hold down the control key and hit the key combination. Works on the whole document, a specific line, or a selection of code.
Go to Definition (F12) Navigate to the definition of the method or variable. Super useful.
Find all References (Shift + F12)
Update References/ Add Using Statement (Ctrl +. or Shift +Alt +F10) I'm referring to the underline that appears under a variable to perform an action like add a using statement, or refacter a method or class name. Not sure what it's called but I use it all the time. Ex: ClassName
List Members (Ctrl +J or Ctrl +K, L) Displays the autocomplete list for classes, methods, or properties.
List Parameter Info (Ctrl +Shift +Space or Ctrl +K +P) Lists the parameters for a method. Use this shortcut when your cursor is inside the parenthesis of a method.
Quick Watch (Ctrl +Alt +Q) Highlight some code and hit these shortcut keys to display the Quick Watch dialog.
Comment / Uncomment (Ctrl +K, C / Ctrl +K, U) Comments or uncomments a block of code. Works with C#, VB, ASPX.
Code Bookmarks Use these to bookmark a line of code. You can cycle through the bookmarks across any file within a project. Bookmarks come in very handy, try it out.
Set/Unset Bookmark (Ctrl +K, K) Next Bookmark (Ctrl +K, N)
Surround With (Ctrl +S) Surrounds a block of code with a code snippet.
Build & Debug Shortcuts Set/Unset Breakpoint (F9) Build (F6 or Ctrl +Shift +B) Start Debugging (F5) Start Without Debugging (Ctrl +F5) Stop Debugging (Shift +F5) Continue (F5) Step Over (F10) Step Into (F11) Step Out (Shift +F11) Attach to Process (Ctrl + Alt + P)
That's it for now, feel free to add more in the comments below. I'll try to update this post periodically.